NovaAtom-Lite leads FoldBench interface tests
Geodesic Intelligence introduced NovaAtom-Lite, an all-atom structure-prediction model for proteins, nucleic acids, and bound molecules. It reports 79.07% antibody–antigen success and 77.06% protein–ligand success on FoldBench, ahead of AlphaFold 3 and IsoDDE on those tasks. [Announcement](https://www.geodesiclab.com/news/introducing-novaatom-lite)
NovaAtom-Lite’s real story is interface prediction, where drug-discovery value is highest and the field remains less solved than monomer folding.
- –It leads antibody–antigen and protein–ligand tests, but not every FoldBench task.
- –Protein monomer scores are effectively saturated, making interface gains more consequential.
- –Test-time sampling improves results, though higher accuracy requires additional compute.
- –Results are company-reported, with some baseline scores drawn from separate evaluations and differing sample counts.
- –An API makes the model immediately useful for computational drug-discovery workflows. [API](https://www.geodesiclab.com/api)
DISCOVERED
11m ago
2026-11-10
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1h ago
2026-11-10
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